Polymer-Supported Oxidovanadium(IV) Complexes and Their Catalytic Applications in One-Pot Multicomponent Reactions Producing Biologically Active 2,4,5-Trisubstituted-1H-imidazoles

Two new monobasic tridentate O?N?N donor ligands, HL1 (I) and HL2 (II) have been obtained in two steps by reacting phenylhydrazine salicylaldehyde or 3,5-di-tert-butylsalicylaldehyde then the resulting compounds with 2-chloromethylbenzimidazole presence of triethylamine. The reaction [VIVO(acac)2] these ligands a 1:1 molar ratio dry methanol led to formation homogeneous oxidovanadium(IV) complexes [VIVO(acac)L1] (1) [VIVO(acac)L2] (2). Immobilization on chloromethylated polystyrene (PS-Cl) cross-linked divinyl benzene resulted corresponding polymer-supported heterogeneous PS-[VIVO(acac)L1] (3) PS-[VIVO(acac)L2] (4). Ligands (I II), (1 2) (3 4) characterized using elemental analysis various spectroscopic techniques. A single crystal X-ray diffraction study I 1 further confirms their structures. oxidation state IV vanadium was assured recording EPR spectra while were field emission-scanning electron microscopy (FE-SEM) combined energy dispersive (EDS) atomic force (AFM). All explored for catalytic potential one-pot-three-component reactions (reagents: benzil, ammonium acetate aromatic aldehydes) efficient synthesis 2,4,5-triphenyl-1H-imidazole derivatives (nine examples). Various conditions optimized obtain maximum yield (up 96%) products. It has found that show excellent activity are recyclable up five cycles.